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Dr Farzana Khan

Dr Farzana Khan

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Dr Farzana Khan qualified as an MD from the University of Copenhagen in 2003. She has worked in dermatology and obstetrics & gynaecology across the North of England and completed her MRCGP (CCT, 2013) and the Diploma of the Faculty of Sexual & Reproductive Health (2013). Her clinical focus is vaginal health—including dryness/GSM, sexual function concerns, lichen sclerosus, and comfort or volume changes. She offers careful assessment, discusses medical and conservative options first, and considers selected regenerative or aesthetic treatments where appropriate. Dr Farzana also trains clinicians as a KOL/Trainer with Neauvia, Asclepion Laser, and RegenLab (since 2023). Ongoing CPD includes IMCAS, CCR, ACE and expert training in women’s intimate fillers, PRP, and polynucleotide injectables. Her approach is simple: clear explanations, realistic expectations, and shared decision-making. Authored and medically reviewed by Dr Farzana Khan.

MD MRCGP DFFP
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Dryness & GSM faq

Can stress or low oestrogen trigger dryness flares?

Yes. Falling oestrogen during peri- and post-menopause lowers natural lubrication and raises vaginal pH; stress can further reduce arousal and exacerbate friction, making genitourinary syndrome of menopause (GSM) symptoms flare. Flares often follow illness, disrupted sleep, travel, or high-friction activity. Gentle vulval care, regular moisturisers and the right lubricant help; persistent symptoms often improve with local vaginal oestrogen or DHEA after assessment. Educational only. Results vary. Not a cure.

Clinical Context

Who is more prone to flares? Those in late perimenopause or post-menopause; people after surgical menopause; individuals with sensitive skin or dermatoses; and anyone who pauses regular moisturiser routines during travel or illness. High-friction activities (distance cycling, running) can unmask symptoms. Medications with drying or anticholinergic effects (some antidepressants, antihistamines, bladder antimuscarinics) can compound dryness; discuss alternatives if symptoms are severe.

Who should seek review first? If symptoms recur despite consistent basics; if there is new malodorous or clumpy discharge, fever, pelvic pain; visible ulcers/white patches; visible blood in urine; or post-menopausal bleeding. People with a history of hormone-sensitive cancers should discuss local oestrogen or vaginal DHEA with their oncology and menopause teams. Alternatives for those avoiding hormones include scheduled non-hormonal moisturisers/lubricants, pelvic floor physiotherapy, and psychosexual support. Plan review after 6–12 weeks to adjust to the lowest effective maintenance once comfortable.

Evidence-Based Approaches

UK guidance recommends a step-wise pathway. The NICE Menopause Guideline (NG23) advises offering information on vaginal moisturisers and lubricants, and considering low-dose local vaginal oestrogen when GSM affects quality of life. Many continue long-term maintenance at the minimum effective dose, regardless of systemic HRT use.

Randomised trials summarised in the Cochrane Library show that low-dose vaginal oestrogens improve dryness, soreness, dyspareunia and vaginal pH compared with placebo, with broadly similar efficacy between creams, pessaries/tablets and rings, and low systemic absorption at licensed doses. A peer-reviewed overview of GSM terminology, mechanisms and options (including vaginal DHEA and non-hormonal moisturisers such as hyaluronic acid) is indexed on PubMed.

For prescribing details and cautions on UK products, consult the British National Formulary (BNF). Patient-facing advice on symptoms, self-care and when to seek help is available from the NHS: see NHS guidance on vaginal dryness. Together, these sources support a practical plan: build reliable moisturiser/lubricant routines; add local oestrogen or DHEA when needed; address pelvic floor and psychosexual factors; and reserve device-based or regenerative options for selected cases after a shared decision-making discussion. ® belongs to its owner.