Does gabapentin work for menopausal hot flushes?
Yes, gabapentin, a medication often used for nerve pain, can help reduce the frequency and severity of menopausal hot flushes, especially when HRT is not suitable.
Detailed Medical Explanation
Gabapentin is not a hormone but has been shown in clinical trials to significantly reduce hot flushes in menopausal women. It is especially helpful for women who cannot take HRT or have night sweats disturbing sleep. Side effects may include drowsiness or dizziness. Gabapentin should only be used under medical supervision. Read more in the BNF menopause summary.
Clinical Context
Gabapentin may be particularly suitable for women with severe night sweats or contraindications to HRT. It is recommended in NICE guidance as a non-hormonal option for hot flushes.
Evidence-Based Approaches
Multiple randomised controlled trials show gabapentin can reduce hot flushes by up to 50%. Monitoring for side effects and regular follow-up are advised. For official recommendations, see NICE menopause guidance.
