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womens health clinic faq

What generic UTI antibiotics are available?

Common generic antibiotics for UTIs in the UK include nitrofurantoin, trimethoprim, amoxicillin, cefalexin, and fosfomycin—all widely available and inexpensive.

Clinical Context

Nitrofurantoin and trimethoprim are the most commonly prescribed first-line treatments. Others may be used if there are allergies, pregnancy or known resistance patterns.

Evidence-Based Approaches

NICE NG109 recommends prescribing based on local antimicrobial sensitivity data. Nitrofurantoin typically has much lower resistance rates (~3%) compared to trimethoprim (~30%) (nice.org.uk).