Can autoimmune diseases cause vaginal atrophy?
Some autoimmune diseases can contribute to vaginal atrophy, especially those that affect hormone levels or directly target mucosal tissues, such as Sjögren’s syndrome and premature ovarian insufficiency.
Detailed Medical Explanation
Autoimmune conditions like Sjögren’s syndrome can cause dryness throughout the body, including the vagina. Others, like systemic lupus or premature ovarian insufficiency, can impact hormone levels, leading to earlier or more severe atrophy. Management should be tailored to the underlying condition. NHS: Sjögren’s Syndrome | NHS: Premature Ovarian Insufficiency.
Clinical Context
Women with autoimmune disorders and new symptoms of dryness or discomfort should seek early assessment for possible atrophy.
Evidence-Based Approaches
Guidelines recommend considering autoimmune and endocrine causes in unexplained vaginal atrophy. RCOG: Atrophy & Underlying Disease.