CO2 resurfacing
Safety first
Women’s Health Clinic FAQ
What should I do to prepare my skin before CO2 laser resurfacing?
Good preparation helps your skin enter treatment calm, untanned and medically assessed. CO2 laser resurfacing creates a controlled wound, so the weeks beforehand are about reducing avoidable irritation, pigment risk and infection risk.
Direct answer
Prepare your skin by following the plan given at consultation: avoid tanning and strong sun, disclose all medicines and supplements, pause irritating actives such as retinoids or exfoliating acids when advised, and tell the clinic about cold sores, recent illness, active acne, eczema or poor healing. Arrive with clean skin and have your recovery supplies ready at home. Do not stop prescribed medicines unless your clinician or GP tells you to. Suitability is confirmed after assessment.
Your exact preparation may vary with treatment depth, skin tone, medical history and whether sedation or local anaesthetic is planned. If anything changes before treatment, including illness, a cold sore tingle or recent sun exposure, contact the clinic before attending.
Educational only. This FAQ is general information and does not replace your personalised pre-treatment instructions. Results vary. Not a cure.

At a glance
Most preparation steps fit into four themes: medical screening, skin barrier calm, pigment prevention and practical recovery planning.
At a glance
Before CO2 laser resurfacing
Sun and tan
Avoid sunburn, sunbeds and fake tan before treatment.
Medication review
Disclose medicines, supplements and cold sore history.
Skincare pause
Stop retinoids, acids or scrubs only as advised.
Treatment day
Arrive clean-faced with transport planned if needed.
Do not self-adjust prescriptions
Some medicines affect healing or sensitivity, but prescribed medicines should only be changed with clinician or GP guidance.
Medication check
Cold sore plan
Barrier care
Clean skin
Detailed answer
Preparation is about making the skin predictable
CO2 laser energy targets water in the skin, removes damaged surface tissue and heats the dermis to trigger collagen remodelling. Preparation reduces avoidable inflammation before this controlled injury.
A calm barrier heals more reliably
When the skin is sunburnt, recently tanned, irritated by actives or inflamed by infection, the risk of pigment change, delayed healing and discomfort can rise. A simple routine is often safer before treatment.
Pigment risk
HSV screening
Collagen repair
Medical screening
Your clinician should review medical history, skin type, pregnancy or breastfeeding status, tendency to keloids, active skin disease, recent medicines and previous reactions to procedures.
Pigment control
Recent tanning, sunburn and melasma tendency can increase post-inflammatory hyperpigmentation risk. Some patients need clinician-led pigment preparation and more conservative settings.
Skincare simplification
Retinoids, exfoliating acids, scrubs and new products can make skin more reactive. Many protocols pause these in the final days before treatment, but timings should be individualised.
Healing readiness
Sleep, hydration, nutrition, avoiding smoking where possible and preparing aftercare supplies all support the early wound-healing phases of re-epithelialisation and collagen signalling.
A useful preparation timeline
Four to six weeks before, focus on consultation, sun avoidance and identifying pigment or healing risks. One to two weeks before, simplify skincare and confirm medication guidance. In the final 48 hours, avoid heat, alcohol and strenuous exercise if your clinic advises this.
On the day, arrive with clean skin and no makeup, fake tan, heavy creams or facial oils on the treatment area. Bring your medicine list and arrange a lift home if sedation or stronger pain relief is planned.
Patient safety
Why preparation matters
Preparation does not guarantee a specific result, but it can reduce avoidable risk and make the clinical plan safer and more predictable.
Pigment changes
Sun exposure and heat-sensitive skin can make darkening or uneven colour more likely after resurfacing, especially in darker or pigment-prone skin.
Infection prevention
Active infection, cold sore symptoms or broken skin should be flagged before treatment because resurfacing temporarily weakens the skin barrier.
Medication safety
Some medicines and supplements can affect bruising, light sensitivity or healing. Disclosure matters, but prescribed medicines should not be stopped without advice.
Realistic recovery
Having cleansing, ointment, sun protection, time off and follow-up details ready makes the first days less stressful and supports proper wound care.
The biology underneath the checklist
CO2 laser creates microscopic heat injury. Keratinocytes then close the surface while fibroblasts produce new collagen. Irritation, infection, nicotine exposure, uncontrolled inflammation or UV exposure can interfere with that repair sequence.
In perimenopause and menopause, skin may feel drier or less resilient. Oestrogen is relevant to collagen and barrier biology, but any hormone-related treatment decisions must stay within a personalised medical consultation.
Considerations
What to do before your appointment
Use these preparation areas as a structured conversation with your clinician. Your own instructions may be stricter depending on treatment depth and medical history.
Tell the clinic early
Contact the clinic if you develop illness, an active spot, cold sore symptoms, sunburn, a new medicine, a rash or any change that may affect treatment safety.
7-10 days
48 hours
Treatment day
4-6 weeks before
Book assessment, avoid tanning and sunbeds, start daily SPF, disclose skin history and ask whether pigment-calming preparation is appropriate for your skin tone.
1-2 weeks before
Avoid active facials, peels, waxing or harsh exfoliation on the treatment area. Confirm what to do with retinoids, acids, supplements and photosensitising medicines.
48 hours before
Prioritise sleep and hydration. Avoid alcohol, saunas, heat exposure and strenuous exercise if advised. Make sure bland cleanser, ointment and clean towels are ready.
On the day
Arrive with clean skin, no makeup, no fake tan and no facial oils on the area. Bring your medicine list and wear clothing that does not need pulling over the treated face.
Aftercare starts before treatment
Ask who to contact out of hours, when your review is planned, when you can cleanse, what ointment to use, when SPF can be applied and when active skincare can restart.
If fees, appointment length, anaesthetic plan or aftercare inclusions are unclear, please refer to the /pricing/ page or confirm details before booking.
Common concerns and myths
Preparation myths to avoid
The safest preparation advice is practical, specific and personalised. Avoid shortcuts that make the skin more reactive.
Myth: It is just skincare
Preparation also includes medical history, medicines, infection risk, transport, downtime, sun exposure and follow-up access. The skin routine is only one part of safety.
Myth: A light tan is fine
Tanned or sunburnt skin is more reactive and may be more likely to pigment unevenly. Treatment may need to be postponed until the skin has settled.
Myth: Strong actives help right up to treatment
Retinoids and acids can be useful long term, but close to ablative laser they may increase irritation. Pause and restart timings should follow your clinician’s plan.
What if I get a cold sore?
Tell the clinic straight away if you notice tingling, soreness or blisters. Laser resurfacing can reactivate herpes simplex, so antiviral planning may be needed before treatment proceeds.
What if I have acne or eczema?
Active inflamed skin can raise infection, irritation or uneven healing risk. Treatment is often deferred until the area is calm and a clinician confirms suitability.
Safety checklist
Pre-treatment safety checklist
These are the questions worth answering before your appointment date is confirmed.
Have I disclosed everything?
Share medicines, supplements, allergies, cold sores, recent procedures, pregnancy or breastfeeding, smoking and previous scarring or pigmentation.
Is my skin calm?
Avoid treatment over active infection, cold sores, open skin, severe acne flare, dermatitis, sunburn or recent fake tan.
Do I know what to pause?
Confirm exactly when to pause retinoids, exfoliating acids, scrubs, waxing, peels and any non-essential supplements.
Am I ready for recovery?
Have bland cleanser, prescribed or recommended ointment, clean towels, pillows, sun protection and clinic contact details ready.
Green flags
The plan includes assessment, written instructions, realistic downtime, aftercare supplies, review arrangements and a clear route for concerns.
No recent tan
Clinic contact route
Reasons to pause
Do not proceed without advice if there is active infection, cold sore symptoms, recent sunburn, new medication, unclear instructions or inability to follow aftercare.
Sunburn or tan
Active rash
When to escalate
When to postpone or seek advice
It is safer to delay treatment than to laser over inflamed, infected or recently tanned skin. These issues should be raised before attending. Use NHS 111 online
Active infection or illness
Fever, feeling unwell, spreading rash, impetigo, shingles, open wounds or active cold sores should be reviewed before treatment.
Suspicious skin lesion
Changing, bleeding, crusting, painful, irregular or non-healing lesions need medical assessment before any cosmetic laser is considered.
Recent UV exposure
Sunburn, sunbed use, fake tan or a fresh holiday tan can increase pigment risk and may mean the appointment should move.
Medication uncertainty
If you have started a new medicine, are taking photosensitising treatment or are unsure what to pause, ask before making changes.
Use NHS 111 for urgent advice or call 999 in a life-threatening emergency, including severe allergic symptoms, breathing difficulty, chest pain or sudden severe illness.
More preparation details
What should I buy before treatment?
Ask the clinic for their exact list. Common items include a bland cleanser, recommended ointment, clean soft towels, pillows for head elevation, a wide-brimmed hat and suitable sun protection for when the skin has closed.Should I stop retinoids?
Many protocols pause retinoids and exfoliating acids in the final days before resurfacing. Your timing should be personalised because skin tolerance, treatment depth and prescription use vary.Can I wear makeup on the day?
No. Arrive with clean skin and no makeup, fake tan, heavy moisturiser, sunscreen or facial oils on the treatment area unless your clinic has specifically instructed otherwise.Does menopause change preparation?
Menopause can be associated with drier, thinner or less resilient skin. This does not automatically rule out treatment, but it is worth discussing barrier support, healing expectations and any hormone-related care during consultation.When should I restart normal skincare?
Do not restart retinoids, acids, scrubs or active serums until the skin has re-epithelialised and your clinician has advised that the barrier is ready.What details must be confirmed?
Please confirm medication pauses, antiviral planning, pigment-prep products, anaesthetic plan, transport needs, exact aftercare products and emergency contact details before treatment.Regulatory resources
Authoritative preparation resources
These resources support the safety and preparation guidance used in this FAQ.
NHS laser resurfacing patient leaflet
This NHS Trust leaflet gives practical preparation and aftercare advice, including sun avoidance, medicine disclosure and when to report infection symptoms.
British Cosmetic Dermatology Group leaflet
This UK professional resource explains consultation, suitability, risks, aftercare and who should not have ablative laser resurfacing.
NCBI Bookshelf: CO2 laser resurfacing
This clinical reference outlines CO2 laser resurfacing indications, contraindications, preparation, equipment and complication prevention.
Next step
Prepare with a plan, not guesswork
If you are considering CO2 laser resurfacing, book an assessment so your skin type, medicines, pigmentation risk, cold sore history, downtime and aftercare plan can be checked before treatment.
Educational only. This page is for general education and cannot confirm suitability, diagnose a skin condition or replace personalised medical advice. Results vary. Not a cure.