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womens health clinic faq

What medications can cause dyspareunia as side effect?

Some medications, including certain antidepressants, antihistamines, chemotherapy agents, and hormonal contraceptives, can cause dyspareunia by reducing vaginal lubrication or affecting hormones.

Clinical Context

If you notice pain with sex after starting a new medication, discuss this with your GP or pharmacist. Adjusting medication or using vaginal moisturisers may help.

Evidence-Based Approaches

NHS and BNF guidelines recommend regular review of medication lists in women with new or persistent dyspareunia. Alternative medicines or supportive treatments may be considered. NHS Medicines.