What is the best steroid cream for lichen sclerosus?
The most effective and widely recommended steroid cream for lichen sclerosus is clobetasol propionate 0.05%, a potent topical corticosteroid. It is considered the gold standard for controlling symptoms and preventing complications.
Detailed Medical Explanation
Clobetasol propionate 0.05% ointment is the first-line treatment for lichen sclerosus, recommended by national and international guidelines. Its strong anti-inflammatory action quickly reduces itching, soreness, and skin changes. Other steroids, such as mometasone or betamethasone, may be used in milder cases or for maintenance, but clobetasol remains the most researched and effective option. The regimen and duration should be guided by a specialist. See official guidance at NICE BNF and British Association of Dermatologists.
Clinical Context
Correct use of potent steroid ointment under medical supervision leads to rapid symptom relief and reduces risk of scarring or cancer. Our clinic provides personalised treatment plans and monitoring: Vulval Skin Conditions Clinic.
Evidence-Based Approaches
Clobetasol propionate 0.05% ointment has the strongest clinical evidence. Use should be followed by regular check-ups and ongoing education for long-term management. For dosing schedules, see NICE BNF.