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womens health clinic faq

What is ospemifene (Osphena) for vaginal atrophy?

Ospemifene (Osphena) is a non-hormonal oral medication for the treatment of moderate to severe vaginal atrophy, particularly in women who cannot use oestrogen. It acts as a selective oestrogen receptor modulator (SERM) to improve vaginal health and reduce pain during sex.

Clinical Context

Ospemifene offers an option for women needing a non-oestrogen systemic therapy for atrophy, under specialist supervision.

Evidence-Based Approaches

Ospemifene is supported by international guidelines as a secondary option for moderate-severe atrophy when local therapy is not suitable. RCOG: SERM Therapy.