How to use clobetasol propionate for lichen sclerosus?
Clobetasol propionate 0.05% ointment should be applied thinly to affected areas, usually once daily for up to 12 weeks, then less frequently for maintenance. Always follow your specialist’s instructions and avoid overuse.
Detailed Medical Explanation
The standard protocol involves applying a thin layer of clobetasol propionate ointment to clean, dry skin, covering only the areas with lichen sclerosus. For the initial phase, daily application is recommended, followed by a reduction to alternate days and then to twice weekly for long-term maintenance. Using the fingertip unit method can help avoid excess use. Do not use on broken skin or healthy tissue. Prolonged, unsupervised use can lead to side effects. Always consult your healthcare provider for tailored advice. Official guidance: NICE BNF | NHS medicines information.
Clinical Context
Correct technique and adherence are essential for good outcomes. Our clinic educates women on application, monitoring, and safe long-term use: Vulval Skin Conditions Clinic.
Evidence-Based Approaches
Clinical trials confirm the efficacy of clobetasol when used as prescribed. Maintenance dosing reduces relapse. See NICE BNF and British Association of Dermatologists.