Does D-mannose work for UTI prevention?
D-mannose, a type of sugar, has some evidence for reducing the risk of recurrent UTIs, especially in women. It may prevent E. coli bacteria from attaching to the bladder wall.
Detailed Medical Explanation
Clinical studies suggest D-mannose may lower the risk of recurrent UTIs, particularly in women who have frequent infections. It is believed to work by preventing E. coli from adhering to the bladder lining, allowing the bacteria to be flushed out. While promising, it should not replace standard treatments for an active infection. NHS: D-mannose and UTI.
Clinical Context
Clinics may suggest D-mannose as a preventive supplement for women with recurrent UTIs, especially when other measures have failed. Safety and dosing should be discussed with your clinician.
Evidence-Based Approaches
NHS and NICE recognise the emerging evidence for D-mannose but advise it as adjunct only. It should not be used to treat an active infection.