Can chemotherapy cause vaginal numbness?
Yes, chemotherapy can cause vaginal numbness as a result of nerve damage (peripheral neuropathy) and hormonal changes, leading to reduced sensation and dryness.
Detailed Medical Explanation
Certain chemotherapy drugs can cause peripheral neuropathy, damaging nerves that supply the pelvic and genital region. Chemotherapy can also lower oestrogen, leading to thinning and dryness of vaginal tissues. These effects can cause numbness, tingling, and discomfort. Symptoms may improve after treatment, but some may persist. Supportive treatments are available. NHS: Chemotherapy side effects.
Clinical Context
Women receiving chemotherapy who develop changes in sensation should discuss symptoms with their cancer care team. Symptom relief and sexual health support can improve quality of life.
Evidence-Based Approaches
NICE and Macmillan recommend a holistic approach to cancer survivorship, including neuropathy management and vaginal health support (Macmillan: Sex and cancer).