Can photodynamic therapy help with lichen sclerosus?
Photodynamic therapy (PDT) is an emerging option for lichen sclerosus, mainly used when standard treatments are ineffective. Clinical evidence is promising but limited compared to steroid therapy.
Detailed Medical Explanation
Photodynamic therapy involves the application of a photosensitising agent to the affected area, followed by exposure to a specific light wavelength. This process destroys abnormal skin cells and modulates the immune response. Studies show PDT may improve symptoms and appearance in steroid-resistant cases, but further research is needed. It is not routinely available in all centres. More at NCBI – PDT for Lichen Sclerosus and British Association of Dermatologists.
Clinical Context
PDT is generally reserved for women who do not respond to or cannot tolerate standard treatments. Our clinic can discuss suitability and refer as appropriate: Vulval Skin Conditions Clinic.
Evidence-Based Approaches
PDT has shown positive outcomes in small studies but is not first-line. More evidence is needed before widespread adoption. Further reading: NCBI.