What is the best hormone replacement therapy for hot flushes?
Oestrogen-based HRT is considered the most effective treatment for menopausal hot flushes, with combined oestrogen and progestogen therapy used for women with a uterus.
Detailed Medical Explanation
HRT containing oestrogen is proven to be the most effective therapy for relieving vasomotor symptoms such as hot flushes. Women with an intact uterus require a combination of oestrogen and progestogen to protect the endometrium, while women without a uterus can take oestrogen alone. Various formulations (tablets, patches, gels, sprays) are available. The choice of product depends on individual health profile, symptom severity, and personal preference. Read more at NHS HRT page.
Clinical Context
Specialist menopause clinics assess personal risk factors and preferences to determine the most suitable HRT. Factors like age, medical history, and symptom severity influence selection. Years of clinical evidence confirm the effectiveness of HRT for hot flushes.
Evidence-Based Approaches
NICE and NHS recommend individualised HRT regimens. Regular review ensures the lowest effective dose is used. Non-oral forms (patches, gels) may have fewer side effects for some women. See NICE menopause guidance for the latest recommendations.