Can chemotherapy cause vaginal atrophy?
Yes, chemotherapy can cause vaginal atrophy by reducing oestrogen levels or bringing on early menopause, resulting in thinning, dryness, and discomfort of the vaginal tissues.
Detailed Medical Explanation
Chemotherapy can suppress ovarian function or induce menopause, leading to low oestrogen. This causes thinning of vaginal tissues, reduced elasticity, and loss of lubrication. Symptoms can persist after treatment, especially in younger women with early menopause. Macmillan: Cancer and Vaginal Changes.
Clinical Context
Oncology teams frequently counsel women about vaginal atrophy as a side effect of cancer therapy. Early support improves comfort and quality of life.
Evidence-Based Approaches
Guidelines recommend early use of non-hormonal moisturisers and lubricants, and specialist referral when symptoms persist. RCOG: GSM and Cancer.